{"id":433,"date":"2026-01-09T06:53:54","date_gmt":"2026-01-09T06:53:54","guid":{"rendered":"https:\/\/kishiwada.tokushukai.or.jp\/en\/?page_id=433"},"modified":"2026-04-11T03:56:08","modified_gmt":"2026-04-11T03:56:08","slug":"systemic-chemotherapy-colorectal-cancer","status":"publish","type":"page","link":"https:\/\/kishiwada.tokushukai.or.jp\/en\/departments\/lower-gi-surgery\/systemic-chemotherapy-colorectal-cancer\/","title":{"rendered":"Systemic Chemotherapy"},"content":{"rendered":"

<\/p>\n

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<\/p>\n

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Treatment<\/div>\n
Systemic chemotherapy for unresectable colorectal cancer<\/div>\n<\/p><\/div>\n
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Target conditions<\/div>\n
Colon cancer and rectal cancer<\/div>\n<\/p><\/div>\n
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Treatment goal<\/div>\n
Prolong survival while maintaining quality of life<\/div>\n<\/p><\/div>\n<\/p><\/div>\n

\n When colon or rectal cancer is considered unresectable<\/strong>,
\n systemic chemotherapy is introduced based on established clinical guidelines.
\n Treatment aims to control disease progression, improve survival outcomes,
\n and maintain quality of life.\n <\/p>\n

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Overview<\/h2>\n<\/p><\/div>\n
\n

\n Systemic chemotherapy is used for patients with advanced colorectal cancer
\n that cannot be completely removed by surgery at the time of diagnosis.
\n Treatment regimens are selected according to tumour characteristics,
\n molecular profile, and overall patient condition.\n <\/p>\n

\n Treatment plans are individualised and may include combination chemotherapy
\n and targeted agents, in accordance with current clinical guidelines.\n <\/p>\n<\/p><\/div>\n<\/p><\/div>\n

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When surgery may become possible<\/h2>\n<\/p><\/div>\n
\n

\n In some patients, chemotherapy can reduce tumour size and extent.
\n If the disease becomes resectable, curative surgery may be considered<\/strong>.\n <\/p>\n

\n Treatment response is assessed with imaging and clinical evaluation,
\n and surgical options are discussed when appropriate.\n <\/p>\n<\/p><\/div>\n<\/p><\/div>\n

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Supportive care and quality of life<\/h2>\n<\/p><\/div>\n
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\n Chemotherapy is provided alongside supportive care to maintain quality of life.
\n We work in collaboration with the Palliative Care Team<\/strong>
\n to address treatment-related symptoms and overall well-being.\n <\/p>\n

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