{"id":433,"date":"2026-01-09T06:53:54","date_gmt":"2026-01-09T06:53:54","guid":{"rendered":"https:\/\/kishiwada.tokushukai.or.jp\/en\/?page_id=433"},"modified":"2026-04-11T03:56:08","modified_gmt":"2026-04-11T03:56:08","slug":"systemic-chemotherapy-colorectal-cancer","status":"publish","type":"page","link":"https:\/\/kishiwada.tokushukai.or.jp\/en\/departments\/lower-gi-surgery\/systemic-chemotherapy-colorectal-cancer\/","title":{"rendered":"Systemic Chemotherapy"},"content":{"rendered":"<p><!-- Service: Systemic chemotherapy for unresectable colorectal cancer \/ \u5207\u9664\u4e0d\u80fd\u5927\u8178\u304c\u3093\u306b\u5bfe\u3059\u308b\u5168\u8eab\u5316\u5b66\u7642\u6cd5 --><\/p>\n<section class=\"op-section disease\">\n<p>  <!-- Key takeaways --><\/p>\n<section class=\"op-section disease\">\n<div class=\"disease-kpi\">\n<div class=\"disease-kpi__item\">\n<div class=\"disease-kpi__label\">Treatment<\/div>\n<div class=\"disease-kpi__value\">Systemic chemotherapy for unresectable colorectal cancer<\/div>\n<\/p><\/div>\n<div class=\"disease-kpi__item\">\n<div class=\"disease-kpi__label\">Target conditions<\/div>\n<div class=\"disease-kpi__value\">Colon cancer and rectal cancer<\/div>\n<\/p><\/div>\n<div class=\"disease-kpi__item\">\n<div class=\"disease-kpi__label\">Treatment goal<\/div>\n<div class=\"disease-kpi__value\">Prolong survival while maintaining quality of life<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<p class=\"disease-lead\">\n    When colon or rectal cancer is considered <strong>unresectable<\/strong>,<br \/>\n    systemic chemotherapy is introduced based on established clinical guidelines.<br \/>\n    Treatment aims to control disease progression, improve survival outcomes,<br \/>\n    and maintain quality of life.\n  <\/p>\n<div class=\"disease-rows\">\n<div class=\"disease-row\">\n<div class=\"disease-row__h\">\n<h2>Overview<\/h2>\n<\/p><\/div>\n<div class=\"disease-row__b\">\n<p>\n          Systemic chemotherapy is used for patients with advanced colorectal cancer<br \/>\n          that cannot be completely removed by surgery at the time of diagnosis.<br \/>\n          Treatment regimens are selected according to tumour characteristics,<br \/>\n          molecular profile, and overall patient condition.\n        <\/p>\n<p class=\"disease-muted\">\n          Treatment plans are individualised and may include combination chemotherapy<br \/>\n          and targeted agents, in accordance with current clinical guidelines.\n        <\/p>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"disease-row\">\n<div class=\"disease-row__h\">\n<h2>When surgery may become possible<\/h2>\n<\/p><\/div>\n<div class=\"disease-row__b\">\n<p>\n          In some patients, chemotherapy can reduce tumour size and extent.<br \/>\n          If the disease becomes resectable, <strong>curative surgery may be considered<\/strong>.\n        <\/p>\n<p class=\"disease-muted\">\n          Treatment response is assessed with imaging and clinical evaluation,<br \/>\n          and surgical options are discussed when appropriate.\n        <\/p>\n<\/p><\/div>\n<\/p><\/div>\n<div class=\"disease-row\">\n<div class=\"disease-row__h\">\n<h2>Supportive care and quality of life<\/h2>\n<\/p><\/div>\n<div class=\"disease-row__b\">\n<p>\n          Chemotherapy is provided alongside supportive care to maintain quality of life.<br \/>\n          We work in collaboration with the <strong>Palliative Care Team<\/strong><br \/>\n          to address treatment-related symptoms and overall well-being.\n        <\/p>\n<div class=\"disease-callout\">\n<ul class=\"disease-bullets\">\n<li><strong>Symptom management:<\/strong> pain, nausea, fatigue, and other side effects<\/li>\n<li><strong>Daily life support:<\/strong> nutrition, activity, and functional status<\/li>\n<li><strong>Shared decision-making:<\/strong> aligning treatment with patient goals and preferences<\/li>\n<\/ul><\/div>\n<p class=\"disease-muted\">\n          Treatment is adjusted to balance effectiveness, tolerability, and individual priorities.\n        <\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<div class=\"disease-row\">\n<div class=\"disease-row__h\">\n<h2>Appointment<\/h2>\n<\/p><\/div>\n<div class=\"disease-row__b\">\n<p>\n      Appointments are required in principle. A referral letter from another medical institution is recommended but not mandatory.\n    <\/p>\n<p class=\"disease-muted\">\n      For appointment requests and language support, please see the<br \/>\n      <a href=\"\/en\/departments\/lower-gi-surgery\/#contact\">Lower GI Surgery<\/a> page.\n    <\/p>\n<\/p><\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Treatment Systemic chemotherapy for unresectable colorectal cancer Target conditions Colon cancer and rectal cancer Treatment goal Prolong survival while maintaining quality of life When colon or rectal cancer is considered unresectable, systemic chemotherapy is introduced based on established clinical guidelines. Treatment aims to control disease progression, improve survival outcomes, and maintain quality of life. Overview [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":417,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-433","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/pages\/433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/comments?post=433"}],"version-history":[{"count":8,"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/pages\/433\/revisions"}],"predecessor-version":[{"id":1329,"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/pages\/433\/revisions\/1329"}],"up":[{"embeddable":true,"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/pages\/417"}],"wp:attachment":[{"href":"https:\/\/kishiwada.tokushukai.or.jp\/en\/wp-json\/wp\/v2\/media?parent=433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}